Endocrine Abstracts

Two female patients aged 44 (PtA) and 68 years old (PtB) with non-toxic nodular goitre for more than 10 years were treated with radioiodine therapy. High resolution ultrasonography show enlarged thyroid glands 50 ml, with two nodules in left and right lobe in PtA and 58 ml with one nodule in the left lobe in PtB. Serum TSH, fT4 and fT3 were in normal ranges. Malignancy was ruled out by ultrasound-guided fine-needle aspiration biopsy. In PtA thyroid radioi...

Introduction: ACROCOMB is a retrospective Spanish Multicenter study, designed to evaluate the efficacy (extent of tumour control) and safety of lanreotide (LAN) treatment combined with pegvisomant (PEG) or cabergoline in acromegalic patients with monotherapy failure.Methods: patients with acromegaly treated with LAN+PEG (45% of ACROCOMB patients) at 44 Spanish Endocrinology Departments were analysed.Results: 40% of patients were ma...

Introduction: Prolactinomas are more invasive in males. Giant ones (height ≥4 cm) are relatively rare in literature.Our aim is to analyze their frequency, their radiological aspects, and their neurological, endocrine and ophthalmological complications.Methods: All of them had clinical exam, hormonal, ophthalmological, and radiological assessment based on cerebral MRI. Mixed adenomas were excluded. Positive diagnosis was based...

Background: Adipose tissue is considered a highly active metabolic and endocrine organ with important physiological functions. The evaluation of protein expression has the potential advantage of providing a global vision of the cellular pathways associated with adipose tissue dysfunction and obesity, permitting the identification of novel candidate molecules that would have not been considered of interest otherwise.Objectives: To identify proteins differ...

Aim: Evaluation of efficacy and safety of thyroid artery embolization procedure as a method of treatment of hyperthyreosis.Patient and methods: Since May 2004 to July 2005 the thyroid artery embolization procedures have been performed in 9 pts (7 women and 2 men) in mean age 62.3 (44 – 77). The reason for such a treatment were: hyperthyroid goiter with the other organs compression in 5 cases, Graves disease in 2 and thyrotoxicosis type I after amiod...

Adjara is a region in Georgia with high level at iodine deficiency.The aim of the present work was to study the subclinical dysfunctions of thyroid gland in women older than 40 years whose thyroid state hadn’t been examined before.Materials and Methods: From 1998 to 2005 693 women aged 40–78 had been examined. Primary examination was done by different specialists.All women were tested on thyreotropi...

IntroductionContemporary literature highlights the importance of wrist circumference as an easy-to-use marker of general and abdominal obesityMethodsWe measured the wrist circumference and the waist circumference in a heavy volume outpatient department of a specialised endocrine centre in 467 subjects with and without diabetes over a period of one month. Patients with known medical conditions, that were confo...

Implementation strategies for the elimination of iodine deficiency in the last 10 years in Belarus has achieved the WHO evaluation criteria. This was made possible by the universal use of iodized salt in food manufacturing, food service of all types and the availability of its free-trade network salt addition.The aim of this work was to study the iodine daily intake from food, as one of the measures to monitor iodine supply of the population.<p class...

Volume 82, Issue 1, January 2015, Pages 2–11. DOI: 10.1111/cen.12603...

Background: Surgical outcomes in patients with acromegaly are highly dependent on a surgeon’s level of expertise, as the majority of patients present with macroadenomas at diagnosis.Aim: To assess remission rates in patients with acromegaly admitted to a tertiary medical center.Materials and methods: We included patients admitted to the neuroendocrinology and bone disease department with no previous radiation therapy or curren...